In accordance with the “requirements of the guiding opinions on the establishment of a natural reserve system with national parks as the main body”(hereinafter referred to as“the Guiding Opinions”),based on the detailed investigation of all kinds of natural reserves at all levels in the Qinghai Lake Basin,this paper analyzes the problems of overlapping setting,multi management,unclear boundary,unclear rights and responsibilities,prominent contradiction between protection and development,etc.The integration and optimization methods are formulated,and the integration and optimization proposals are put forward and discussed.