With the Geographic Information System(GIS) technique,on the basis of the Fractional Vegetation Cover (FVC) of 2000—2013 NOAA/AVHRR(National Oceanic and Atmospheric Administration/the Advanced Very High Resolution Radiometer)images,and through spatial auto-correlation analysis of FVC index,the spatial-temporal changes of vegetation cover was explored from time and space with 1km×1km spatial resolution.The main results were summarized as follows.In recent ten years,FVC index changed significantly in the study area.In Karamay region,oases were mainly distributed in south Karamay of the study area,relatively less in the north Wuerhe area and scattered in Baijiantan area in the central study area.In recent years,in general,the oasis area expanded significantly,Karamay area was the main expansion direction,but in Wuerhe and Baijiantan areas,the oases were rapidly decreased.Desert,which was mainly distributed in the middle and north of the study area,had increased significantly in recent ten years. Expansion of desertification mainly happened in Wuerhe and Baijiantan areas,some oases surrounded by desert had decreased significantly even disappeared.Oasis-desert ecotone,mainly distributed in Karamay area,had been heavily replaced by oases in recent ten years.Comprehensive and objective analysis of the spatial-temporal changes of FVC index in Karamay region is important to promoting sustaining development of study area.