Mainstreaming of biodiversity is one of the most effective measures for biodiversity conservation and sustainable utilization.China has made great progress in the areas of in-situ biodiversity conservation,policy legislation,law enforcement and supervision,but it has not fundamentally contained the overall decline of biodiversity,mainly because biodiversity of China has not yet been fully mainstreamed,especially in the aspects of laws,economy,mechanism,technology and market,etc,which all need to be strengthened.Establishing a national park system is to innovate China’s natural ecological conservation system,including the establishment of a unified,standardized and efficient natural protected area management system,building the natural protected area system with national park as the main body,and the establishment of a new mechanism for the conservation of integrity and authenticity of the natural ecosystem.The establishment of a national park system in China is conducive to achieve the three major goals defined by the Convention on Biological Diversity,including protecting biodiversity,promoting the sustainable utilization of biodiversity components,and sharing the commercial benefits of genetic resources in a fair and reasonable manner.Judging from the national park system pilots that have been carried out,the 10 pilot sites have effectively led the mainstreaming process of biodiversity conservation in China.To this end,it is necessary to accelerate the establishment of a national park system,provide safeguard in laws,systems,and mechanisms,and form a long-term mechanism for mainstreaming biodiversity in terms of maintaining the boundaries of ecological security,as well as ecological governance,ecological compensation,and realizing the value of ecological products.